Optimisation of multi-omics MALDI-MSI of lung tissue from mucopolysaccharidosis (MPS) disease murine models (#153)
Yuen Tung Ngai
1
,
Matthew Briggs
1
,
Emma Parkinson-Lawrence
1
,
Leigh Donnellan
1
,
Parul Mittal
1
,
Manuela Klingler-Hoffmann
1
,
Sandra Orgeig
1
,
Peter Hoffmann
1
- Clinical & Health Sciences, University of South Australia, Adelaide, SA, Australia
Publish consent withheld
- Bush, D., et al., Neonatal Onset Interstitial Lung Disease as a Primary Presenting Manifestation of Mucopolysaccharidosis Type I. JIMD reports, 2019. 43: p. 71-77.
- Paget, T.L., et al., Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse. Cells, 2021. 10(4).
- Chiang, J., et al., Tachypnea of infancy as the first sign of Sanfilippo syndrome. Pediatrics, 2014. 134(3): p. e884-8.
- Carter, C.L., et al., MALDI-MSI spatially maps N-glycan alterations to histologically distinct pulmonary pathologies following irradiation. Scientific Reports, 2020. 10(1): p. 11559.