Poster Presentation 28th Annual Lorne Proteomics Symposium 2023

Optimisation of multi-omics MALDI-MSI of lung tissue from mucopolysaccharidosis (MPS) disease murine models (#153)

Yuen Tung Ngai 1 , Matthew Briggs 1 , Emma Parkinson-Lawrence 1 , Leigh Donnellan 1 , Parul Mittal 1 , Manuela Klingler-Hoffmann 1 , Sandra Orgeig 1 , Peter Hoffmann 1
  1. Clinical & Health Sciences, University of South Australia, Adelaide, SA, Australia
Publish consent withheld
  1. Bush, D., et al., Neonatal Onset Interstitial Lung Disease as a Primary Presenting Manifestation of Mucopolysaccharidosis Type I. JIMD reports, 2019. 43: p. 71-77.
  2. Paget, T.L., et al., Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse. Cells, 2021. 10(4).
  3. Chiang, J., et al., Tachypnea of infancy as the first sign of Sanfilippo syndrome. Pediatrics, 2014. 134(3): p. e884-8.
  4. Carter, C.L., et al., MALDI-MSI spatially maps N-glycan alterations to histologically distinct pulmonary pathologies following irradiation. Scientific Reports, 2020. 10(1): p. 11559.